Primary extranodal marginal zone Bcell lymphoma of hard palate: A case report

نویسندگان

  • Arpan K Shah
  • Mahesh H Gabhane
  • Meena M Kulkarni
چکیده

Introduction: MALT (mucosa associated lymphoid tissue) lymphomas comprise a heterogeneous group, originally thought to be derived from the marginal zone B­cells that are found surrounding B­cell follicles and within the adjacent lymphoepithelium. They arise most commonly in extranodal organs such as the stomach, major salivary glands and thyroid. Thus, they can be precisely described as extranodal marginal zone B­cell lymphomas (ENMZL). Here, we report a case of MALT lymphoma arising in the palatal minor salivary glands. Case Report: A 55­year­old woman presented with two years history of a left posterior palatal mass. Clinical investigations of the case included computed tomography (CT) scan for the assessment of bone destruction and possible intra­maxillary extension. Histopathological features and immunohistochemistry findings were consistent with the diagnosis of extranodal marginal zone B­cell lymphoma of MALT type. The lesion was treated by complete surgical excision and followed for two years. Conclusion: Even though oral localization of ENMZL is rare, it should be included in the differential diagnosis of benign­ appearing swellings of oral cavity.

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تاریخ انتشار 2012